These models were 3D printed, and a silicone mould was created from them. Based on these data, the program generated digital models of the right 3rd, 4th, and 5th ribs. The patient's age, weight, height, and sex, as well as the number and side of the ribs of interest, were the inputs to the program. Prior to surgical resection, a statistical shape model of human ribs was created and used to synthesise rib models in the software MATLAB (MathWorks, Natick, MA, USA). A 64-year-old male was diagnosed with non-small-cell lung cancer originating in the right upper lobe and invading the lateral aspect of the 3rd, 4th, and 5th ribs. This report presents the first clinical case where patient-specific rib prostheses were created using a computer program and statistical shape model of human ribs. Management of chest wall defects after oncologic resection can be challenging, depending on the size and location of the defect, as well as the method of reconstruction. 3Department of Radiology, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom.2Department of Thoracic Surgery, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom.1Department of Surgical & Interventional Engineering, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom.Pontiki 1* Savvas Lampridis 2 Sara De Angelis 1 Pablo Lamata 1 Richard Housden 1 Giulia Benedetti 3 Andrea Bille 2,† Kawal Rhode 1,†
